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Can Gene Therapy Help Fight Manic Depression

18 January 2010

Those who suffer from bipolar disorder are continuously cycling through bouts of mania and depression that affects them the rest of their lives.

Determining what causes bipolar 1 disorder sickness has long been the focus of many studies. But scientist may finally be getting closer to the crux of the problem.

For years, scientists have suspected a link between genes and manic depression. But there has been no peer studies to prove their point. But recent research points specifically to two genes that seem as though they may play a central part in determining a person’s risk for developing manic depression.

If the discovery turns out to be true, it may potentially lead to a whole host of new and better treatments to combat the disorder.

The 2 genes that are responsible for all of the symptoms of manic depression are the ANK3 gene and the CACNA1C gene. The ANK3 gene is located on chromosome 10 at position q21. The CACNA1C gene is important in the production of the calcium channels which can be found in many of the body’s cells. These cells are particularly important to the operating of the heart and brain cells.

Moreover, it’s known that the proteins created by these genes indirectly influences the activity in the brain’s nerve cells by controlling the flow of sodium and calcium in the brain.

And now, after having discovered the specific genes responsible for bipolar disorder, scientist can begin working on treatments and cures that target the gene directly.

You can read more of Julie’s articles about disquieting symptoms of manic depression and related subjects at her website.

Disclaimer: The medical info published on our website is in no way to be construed as a substitute for informed medical advice. You should not take any action based on information without consulting with a health care professional.

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